Service Description:
The exome (the protein-coding region of the human genome) represents less than 2% of the genome, but contains ~85% of known disease-related variants, For this reason, sequencing of the whole exome has the potential to uncover higher yield of relevant variants at a far lower cost than whole genome sequencing. Whole exome sequencing is thought to be an efficient and powerful way to identify the genetic variants that affect heritable phenotypes, including important disease-causing mutations and natural variations.
Omics Drive employs the Illumina HiSeq and Novaseq system to provide the fast and accurate whole exome sequencing and bioinformatics analysis. Our highly experienced expert team executes quality management, following every procedure to ensure reliable results.
Advantages of Whole Exome Sequencing:
Identifies variants across a wide range of applications
Lower cost and wide availability
Achieves deeper coverage of coding regions
A smaller and more manageable data set for faster and easier analysis compared to whole genome sequencing
Sequencing Platforms:
HiSeq 4000/HiSeq X Ten/NovaSeq 6000
Bioinformatics Analysis:
Data quality control
Alignment with reference genome
SNP/ InDel calling, statistics and annotation
Somatic SNP/ InDel calling, statistics and annotation
...
(More analysis upon request)
Analysis Flow:
